HC

Human challenge study

Topic

Heard in 1 episode across 1 show since Jul 2026

A human challenge study, also known as a challenge trial or controlled human infection model (CHIM), is a type of clinical trial for a vaccine or other pharmaceutical that involves intentionally exposing test subjects to the pathogen or condition being tested. These studies are designed to quickly and efficiently evaluate the efficacy of medical interventions, though they remain ethically controversial due to the deliberate exposure of volunteers to potential health risks.

Learn more

Episodes

1
across 1 show

First heard

Jul 2026

Expert statements

1
1 negative

Episodes per month

Public PodLume episodes featuring it, over the last year.

Show the data
MonthEpisodes
Nov 20250
Dec 20250
Jan 20260
Feb 20260
Mar 20260
Apr 20260
May 20260
Jun 20260
Jul 20261
Aug 20260
Sep 20260
Oct 20260

What experts have said about Human challenge study

1 statement · 1 negative

  1. Bilal KharouniNegativeJul 22, 2026· This Week in Startups

    Deliberately infecting healthy people for medical research crosses Bilal Kharouni’s ethical boundary.

    “the ethical question of getting someone sick, even if you can advance the research, is maybe like a border that I would not cross”

    Listen at 20:07

    Open the episode · Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315
Filter the statements →

Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.

Episodes

1 episode featuring Human challenge study, newest first

Human challenge study · PodLume