Microdosing

Heard in 2 episodes across 2 shows since Jun 2026

Microdosing involves the administration of sub-therapeutic doses of drugs to study their safety, pharmacokinetics, and potential therapeutic benefits in humans. Often conducted as a "Phase 0 study" before Phase I clinical trials, it aims to gather preliminary data without producing significant physiological effects. This technique helps researchers efficiently identify viable drug candidates while reducing the resources spent on non-viable compounds.