Mitochondrial Pyruvate Carrier
TopicHeard in 1 episode across 1 show since Sep 2026
The mitochondrial pyruvate carrier (MPC) is a multi-subunit protein complex located in the inner mitochondrial membrane that facilitates the transport of pyruvate from the cytosol into the mitochondrial matrix. By bridging cytosolic glycolysis with mitochondrial oxidative phosphorylation, the MPC acts as a critical metabolic gatekeeper in eukaryotic energy metabolism. It is primarily composed of two homologous proteins, MPC1 and MPC2, and serves as a key therapeutic target for metabolic, cardiovascular, and neurodegenerative diseases.
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| Month | Episodes |
|---|---|
| Nov 2025 | 0 |
| Dec 2025 | 0 |
| Jan 2026 | 0 |
| Feb 2026 | 0 |
| Mar 2026 | 0 |
| Apr 2026 | 0 |
| May 2026 | 0 |
| Jun 2026 | 0 |
| Jul 2026 | 0 |
| Aug 2026 | 0 |
| Sep 2026 | 1 |
| Oct 2026 | 0 |
What experts have said about Mitochondrial Pyruvate Carrier
1 statement · 1 positive
MPC transports pyruvate into mitochondria.
“MPC. Aptly named, is the carrier that enables pyruvate to get into the mitochondria”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 53:24
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.
Episodes
1 episode featuring Mitochondrial Pyruvate Carrier, newest first
