RI

RNA-mediated inheritance

Topic

Heard in 1 episode across 1 show since Sep 2026

RNA-mediated inheritance is a form of transgenerational epigenetic inheritance where non-coding RNA molecules, such as small interfering RNAs (siRNAs), microRNAs, and tRNA fragments, transmit phenotypic information across generations without altering the underlying DNA sequence. This mechanism allows environmental influences, such as stress or nutritional changes, to be biologically communicated from parents to offspring through germline RNA payloads.

Episodes

1
across 1 show

First heard

Sep 2026

Expert statements

1

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What experts have said about RNA-mediated inheritance

1 statement · 1 neutral

  1. Oded RechaviNeutralSep 10, 2026· Huberman Lab Essentials

    RNA-mediated inheritance requires a protein that carries RNA between generations.

    “If you don't have the protein that physically carries the RNA between generations, it doesn't happen.”

    Listen at 29:53

    Open the episode · Essentials: Genes & the Inheritance of Memories Across Generations | Dr. Oded Rechavi
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Episodes

1 episode featuring RNA-mediated inheritance, newest first