What podcasts say about Alex Marson
Every statement, with the speaker, the exact quote and the moment it was said.
What Alex Marson has said on podcasts
42 statements · 21 positive · 18 negative · 3 neutral
CAR T cells can direct T cells against cancer cells
“those cars are directed to go against cancers”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 0:26
Modern medicine can program cell behavior more precisely than before
“medicine is programming the behavior of cells in a way that's much more directed than was ever conceivable before”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 4:29
Thymic negative selection eliminates T cells recognizing self targets
“If the T cell engages a natural target in the thymus, those cells will die”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 11:44
B cells produce antibodies while coordinating with T cells
“B cells are this other type of lymphocyte that work in coordination with T cells and they're the antibody producing cells”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 12:58
A high-fat diet qualitatively changes inflammatory responses in obese mice
“The actual type of inflammation, the cell responses were different in the mice eating a high fat”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 18:10
Allergy-blocking antibodies may fail in obese, high-fat-diet mice
“The normal diet mice would respond favorably to these. They didn't help the mice that had the obese high fat diet response to inflammation.”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 18:44
Early exposure to certain substances helps maintain immune tolerance
“critical early exposure is part of how tolerance is maintained”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 22:07
Peanut exposure can benefit people who are not yet allergic
“There is strong evidence that exposure to peanuts can be beneficial in people who are not yet allergic”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 22:12
Autoimmune disease emerges when immune self-tolerance mechanisms fail
“autoimmune diseases emerge when those normal checks fail”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 23:53
Autoimmune therapies should control immune activity
“our goal therapeutically with drugs is to make sure that we make the immune system under control”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 25:06
Cytokines can produce systemic effects such as fever
“the cytokines can do can influence, can cause the development of fever”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 26:57
Effective antibiotics can cure susceptible bacterial infections
“Antibiotics, when they're used for bacterial infections that are susceptible to them, are a miracle”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 29:04
Antibiotic overuse could undermine future antibiotic effectiveness
“if we overuse them, that window of human history might come to an end”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 29:32
Cancer is a genetic disease involving loss of cellular growth regulation
“It's genetic disease where cells lose the normal regulation and are dividing out of control in various tissues”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 33:21
Smoking increases lung-cell DNA damage and mutation rates
“smoking causes chemicals to go into your lungs, the lung cells get exposed to these chemicals that then cause higher amounts of DNA damage, more mutations”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 36:22
BRCA mutations predispose people to breast and other cancers
“people will likely have heard of the brca or the BRCA genes which predispose to breast cancer and other types of cancer”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 36:51
Ultraviolet exposure increases DNA damage in skin cells
“UV is a risk factor for DNA damage in the skin”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 37:53
Inherited BRCA mutations substantially increase individual cancer risk
“if you inherit a BRCA mutation as an individual, you have a very high risk of developing cancer”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 39:09
BRCA testing is recommended when there is a family cancer history
“That's certainly recommended. If there's a family history of cancer for BRCA mutations”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 39:26
Mutagens almost inevitably increase cancer risk by increasing mutations
“by virtue of the fact that you're causing more mutations, almost inevitably you're also increasing the risk of cancer”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 45:39
Meat may increase colorectal cancer risk
“meat in general has been implicated as a potential carcinogen, especially in colorectal cancer”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 46:05
Cancer cells can rapidly evolve resistance to targeted therapies
“Cancer cells can evolve quickly and can become resistant to these targeted modifications”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 51:55
Checkpoint inhibitors can unleash T cells against some cancers
“for certain types of cancer, it's been absolutely miraculous that if you make a drug that hits the brake on the T cells, the T cells go stronger and they can be unleashed against cancer”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 53:39
CAR T-cell therapy has succeeded against some leukemias and lymphomas
“This has been done for certain types of leukemia and lymphoma, and there's been these amazing success stories”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 56:09
Most cancers become more common later in life
“most cancers, as you said. Exactly as you said, that there's this sort of increase, and they're largely disease of later stages of life”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 1:03:38
CD19 is present on many B-cell leukemias and lymphomas
“CD19 is found on the surface of many a large number of different types of B cell leukemias and lymphomas”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 1:05:06
Cancer immunotherapy research seeks targets selective to cancer cells
“people are thinking about more and more sophisticated ways to look for these targets that are selectively found on the cancer cell and not on the healthy cell”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 1:06:19
CRISPR editing has become increasingly precise at targeted genomic sites
“we've gotten quite good at getting more and more precise to say, okay, we're making these high fidelity cuts at one place”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 1:18:13
CRISPR base editors can change nucleotides without double-strand breaks
“CRISPR base editors that doesn't introduce a double stranded break, but actually changes nucleotides in a more predictable way”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 1:19:44
Engineered viral tropism can target delivery to specific cell types
“People have really advanced engineered tropism, engineering what cells a virus will deliver material to. And that can be dialed in quite precisely now”
Open the episode · Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex MarsonListen at 1:35:22
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.