What podcasts say about Jared Rutter
Every statement, with the speaker, the exact quote and the moment it was said.
What Jared Rutter has said on podcasts
28 statements · 6 positive · 7 negative · 15 neutral
Overenergized mitochondria increase susceptibility to reactive oxygen species generation.
“when that mitochondria is overpowered, that leads to a state that is very susceptible to generation of these reactive species”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 0:37
Accumulated cellular damage is strongly associated with aging.
“the accumulation of that damage over time is certainly correlated strongly with aging”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 7:33
Complex life evolved from the endosymbiotic union of two cells.
“all of complex life evolved from that”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 12:15
Mitochondrial endosymbiosis enabled previously impossible forms of metabolism.
“it enabled a form of metabolism that wasn't possible before”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 12:40
Human mitochondrial genomes are inherited entirely from the mother.
“the mitochondrial genome of you came completely from your mother”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 17:47
Local mitochondrial ATP production improves cellular energy efficiency.
“by having local production, that makes it more efficient”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 20:37
Mitochondria differ across cell types to match each cell’s functional demands.
“virtually every cell in our body has slightly different mitochondria that are particularly suited to the demands of that cell”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 22:14
Intestinal stem cells prioritize biomass production and duplication over ATP generation.
“those stem cells, ATP is not the major demand of those, of those cells. They need to completely duplicate themselves”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 23:39
A single cell can contain distinct mitochondria with different functions.
“in one cell you can have 2 different kinds of mitochondria that have 2 different functions”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 25:29
Insulin causes adipocytes to convert incoming glucose into stored fat.
“that glucose will then be converted through a series of chemical reactions into a fat molecule”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 28:09
Cells allocate food-derived resources toward either energy production or biomass.
“Food can either be converted to energy or it can be converted to biomass”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 35:20
There is little evidence that cancer is transmissible between people.
“There's very little evidence that cancer is infectious”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 43:19
Cancer cells evolve through mutation and selection within the host.
“Cancer cells undergo evolution in the exact same way”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 44:33
MPC transports pyruvate into mitochondria.
“MPC. Aptly named, is the carrier that enables pyruvate to get into the mitochondria”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 53:24
MPC1 and MPC2 occur in organisms containing mitochondria.
“Everything that has a mitochondria has these 2 MPC1 and MPC2 proteins”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 57:12
Cells continuously monitor their available ATP.
“every cell, almost all cells, know how much usable energy, ATP, they have all the time”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:00:52
Glucagon functions as a hormone associated with fasting.
“Glucagon is called a fasting hormone”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:02:50
Glucagon stimulates fat cells to release stored fat.
“It will go to the fat cell, bind to the fat cell, tell the fat cell to take the fat that it has squirreled away and release it”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:02:56
Fat supplies an estimated 70–80% of cardiomyocyte energy extraction.
“in a normal human, I think it's estimated 70 to 80% of the energy extraction that happens in cardiomyocytes and heart muscle cells is happening from fat”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:03:38
The heart can generate ATP from fats, glucose, lactate, ketones, and amino acids.
“the heart, I feel like, is really fascinating because it'll, it'll eat anything. It's an omnivore. Fats, glucose, lactate, ketones, amino acids”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:06:27
Whole-body MPC-deficient mice do not survive until birth.
“they do not survive to birth”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:07:28
Cardiac MPC loss redirects glucose-derived resources toward biomass and pathological heart growth.
“they start making biomass. That, that again, we talked about that, that bifurcation. We've eliminated their ability to make ATP from it, at least as effectively, and instead they make biomass. They grow.”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:10:01
Choosing between pyruvate oxidation and lactate production is a central cellular metabolic decision.
“that decision— burn it, make lactate— I think you could make a very strong argument is one of the most important metabolic decisions that cells are making all the time”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:25:23
Cells generally prioritize burning fatty acids when they are available.
“most cells when they have fatty acids will burn the fatty acids first”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:30:09
Some cancers are molecularly more similar across organs than within the same organ.
“There are some breast cancers that are more similar to some liver cancers than they are to other breast cancers”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:44:59
Cancer cells can readily develop resistance to metabolism-targeting treatments.
“The challenge there again is that it's fairly easy to develop resistance to that”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:48:07
Different metabolic states produce distinct chemical mixtures detectable in breath or scent.
“when a person's doing different metabolism, they're going to be producing different chemicals in different proportions”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:55:48
Overenergized mitochondria contribute to reactive oxygen species damage.
“one of the contributors to that is mitochondria that have too much energy”
Open the episode · How Mitochondria Control Your Metabolism | Dr. Jared RutterListen at 1:57:48
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.