Mesolimbic circuitry
TopicHeard in 2 episodes across 2 shows since Aug 2026
The mesolimbic pathway, also known as the reward pathway, is a key dopaminergic pathway in the brain that connects the ventral tegmental area in the midbrain to the ventral striatum of the basal ganglia in the forebrain. It plays a crucial role in modulating incentive salience, motivation, reinforcement learning, and fear, and is heavily implicated in the neurobiology of addiction, schizophrenia, and depression.
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| Nov 2025 | 0 |
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| Jan 2026 | 0 |
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| Mar 2026 | 0 |
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| Jun 2026 | 0 |
| Jul 2026 | 0 |
| Aug 2026 | 1 |
| Sep 2026 | 1 |
| Oct 2026 | 0 |
What experts have said about Mesolimbic circuitry
3 statements · 2 negative · 1 neutral
Dysfunction in dopamine circuitry can cause profound motivational loss and apathy.
“when that circuitry is not working that you can get profound loss of motivation apathy”
Open the episode · How to Improve Motivation & Overcome Procrastination | Dr. Masud HusainListen at 0:13
Mesolimbic circuitry links motivation signals to brain action systems.
“this circuitry we were talking about, it's called the mesolimbic circuitry that links the basal ganglia to the frontal lobes, is almost like a final common pathway for motivation signals to engage with the action systems of the brain.”
Open the episode · How to Improve Motivation & Overcome Procrastination | Dr. Masud HusainListen at 17:57
Dopamine pathway activation tends to produce wanting rather than satiety.
“when this dopamine pathway is triggered. It tends to create not the sensation or the perception of satiety, of feeling like something is enough, but rather to produce the sensation of wanting more.”
Open the episode · Essentials: Control Sugar Cravings & Metabolism with Science-Based ToolsListen at 12:39
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.
Episodes
2 episodes featuring Mesolimbic circuitry, newest first
