
MDMA
Productby Various illicit manufacturers; no single maker
Heard in 14 episodes across 10 shows since Jul 2026
MDMA (3,4-methylenedioxymethamphetamine) is a synthetic psychoactive substance with entactogenic, stimulant, and minor psychedelic properties. It is commonly associated with tablets sold as ecstasy and crystalline or powder forms sold as molly; these products can contain other substances and carry significant health risks.
Episodes
This week
Expert statements
Share of the conversation
Mentions of MDMA per 1,000 mentions of anything, 7-day rolling, across the podcasts PodLume Trends follows.
Show the data
| Day | Share (7-day) | Mentions |
|---|---|---|
| Jul 22 | 0.99‰ | 1 |
| Aug 19 | 0.03‰ | 1 |
| Sep 1 | 0.06‰ | 2 |
| Sep 3 | 0.12‰ | 2 |
| Sep 4 | 0.16‰ | 1 |
| Sep 7 | 0.21‰ | 1 |
| Sep 11 | 0.07‰ | 1 |
| Sep 17 | 0.06‰ | 1 |
| Sep 18 | 0.09‰ | 2 |
| Sep 24 | 0.08‰ | 1 |
| Sep 28 | 0.05‰ | 1 |
What experts have said about MDMA
7 statements · 6 positive · 1 negative
MDMA is more toxic and depletes serotonin more than methylone.
“It's a little bit more toxic. It depletes your serotonin a little bit more.”
Open the episode · #884: How to Spot 10-Year Trends and Build Billion-Dollar Companies — Kevin Ryan of DoubleClick, MongoDB, Business Insider, and Many MoreListen at 55:51
Current evidence does not show MDMA is neurotoxic.
“MDMA, there is no evidence that it's neurotoxic”
Open the episode · #2553 - Andrew HubermanListen at 16:52
One to several MDMA sessions appear to reduce PTSD symptoms.
“MDMA appears to, in one to a few MDMA sessions, have an anti PTSD effect”
Open the episode · Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan WilliamsListen at 18:25
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.
Episodes
14 episodes featuring MDMA, newest first
- Sep 28, 2026
Pollan asks whether the brain creates consciousnessHuberman Lab EssentialsSep 28, 2026 - Sep 28, 2026
Marriage turns love into negotiation, performance, and maintenanceModern WisdomSep 28, 2026 - Sep 24, 2026
Kevin Ryan bets on durable trends over startup hypeThe Tim Ferriss ShowSep 24, 2026 - Sep 18, 2026
Australia’s psychedelic breakthrough offers advocates a regulatory playbookThe Tim Ferriss ShowSep 18, 2026 - Sep 17, 2026
Achievement cannot manufacture a sense of worthPassion Struck with John R. MilesSep 17, 2026 - Sep 14, 2026
Andrew Huberman explains how neuroplasticity and discipline shape human behaviorThe Joe Rogan Experience: Protect Our ParksSep 14, 2026