MDMA

MDMA

Product

by Various illicit manufacturers; no single maker

Heard in 14 episodes across 10 shows since Jul 2026

MDMA (3,4-methylenedioxymethamphetamine) is a synthetic psychoactive substance with entactogenic, stimulant, and minor psychedelic properties. It is commonly associated with tablets sold as ecstasy and crystalline or powder forms sold as molly; these products can contain other substances and carry significant health risks.

Discussed inBusiness50%Health & Science50%

Episodes

14
across 10 shows

This week

0
episodes on 0 shows

Expert statements

7
6 positive · 1 negative

Share of the conversation

Mentions of MDMA per 1,000 mentions of anything, 7-day rolling, across the podcasts PodLume Trends follows.

0.0‰0.5‰1‰1.5‰Jul 11Aug 2Aug 25Sep 16Oct 8
Show the data
DayShare (7-day)Mentions
Jul 220.99‰1
Aug 190.03‰1
Sep 10.06‰2
Sep 30.12‰2
Sep 40.16‰1
Sep 70.21‰1
Sep 110.07‰1
Sep 170.06‰1
Sep 180.09‰2
Sep 240.08‰1
Sep 280.05‰1

The full trend: rank, tone and why it is trending →

What experts have said about MDMA

7 statements · 6 positive · 1 negative

  1. How to Spot 10NegativeSep 24, 2026· The Tim Ferriss Show

    MDMA is more toxic and depletes serotonin more than methylone.

    “It's a little bit more toxic. It depletes your serotonin a little bit more.”

    Listen at 55:51

    Open the episode · #884: How to Spot 10-Year Trends and Build Billion-Dollar Companies — Kevin Ryan of DoubleClick, MongoDB, Business Insider, and Many More
  2. Current evidence does not show MDMA is neurotoxic.

    “MDMA, there is no evidence that it's neurotoxic”

    Listen at 16:52

    Open the episode · #2553 - Andrew Huberman
  3. One to several MDMA sessions appear to reduce PTSD symptoms.

    “MDMA appears to, in one to a few MDMA sessions, have an anti PTSD effect”

    Listen at 18:25

    Open the episode · Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.

Episodes

14 episodes featuring MDMA, newest first

MDMA · PodLume