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The Megyn Kelly Show

Sep 7, 2026 · 2h 6m

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Huberman turns health optimization into sustainable daily habits

Andrew Huberman on Practical Wellness Tips, the Danger of "If Only" Thinking, and the Important "Protocols" For Life | Ep. 1392

The conversation tests which widely discussed wellness practices are practical, evidence-informed, and sustainable outside extreme optimization culture.

3 key takeaways
  1. 1Morning light, evening darkness, nasal breathing, and caffeine timing form a practical foundation for sleep and focus.
  2. 2The physiological sigh offers a rapid stress-regulation tool, while sensory grounding can restore agency during difficult moments.
  3. 3Failure and frustration can support adaptation when people avoid rumination, “if only” thinking, and unsustainable self-criticism.

Don't miss

Huberman demonstrates the physiological sigh and explains how its breathing pattern can quickly shift the body away from stress.

The brief

Andrew Huberman traces his interest in mental health and human performance through childhood upheaval, mentorship, and the practical science behind his book Protocols.

His sleep advice starts and ends with light: seek daylight soon after waking, manage evening brightness, and treat nasal breathing as a core health habit.

The episode’s clearest practical moment is the physiological sigh—two nasal inhales followed by a long exhale—as a fast way to reduce stress and heart rate.

Huberman and Megyn Kelly challenge online longevity theater, distinguishing useful health information from extreme routines, performative claims, and advice detached from ordinary life.

The broader argument is behavioral rather than maximalist: use movement, hydration, breathing, reflection, and present-moment awareness to build sustainable health routines.

What was said on this episode

42 statements · 25 positive · 13 negative · 3 mixed · 1 neutral

  1. Andrew David Hubermanon Developing brainNegative7:22

    Developing brains are highly susceptible to chemical and environmental inputs.

    “the developing brain is so fragile and so susceptible to both chemical and environmental inputs.”

    Listen at 7:22

  2. Andrew David Hubermanon Knowledge about mental healthNegative11:15

    Knowledge alone is insufficient to protect people from mental-health problems.

    “knowledge alone doesn't save us. Knowledge is important. It's, as we say in science, necessary, but not sufficient”

    Listen at 11:15

  3. Andrew David Hubermanon Daylight and nighttime darknessPositive19:09

    Bright daytime light and dark nights support health and sleep.

    “You want bright mornings and days and dark nights.”

    Listen at 19:09

  4. Andrew David Hubermanon Morning cortisolPositive19:31

    High morning cortisol is beneficial rather than inherently harmful.

    “You want your morning cortisol high. I'll repeat that. You want your morning cortisol high.”

    Listen at 19:31

  5. Andrew David Hubermanon Morning cortisolPositive19:42

    Higher morning cortisol helps lower nighttime cortisol.

    “if you get your morning cortisol high, it helps ensure that your nighttime cortisol is low.”

    Listen at 19:42

  6. Morning daylight amplifies cortisol timing and makes nighttime sleep easier.

    “if you get bright light in your eyes from daylight, from sunlight, it amplifies that cortisol peak, which makes it much lower before sleep, which makes it far easier to fall asleep at night.”

    Listen at 21:23

  7. Andrew David Hubermanon Morning cortisol elevationPositive21:39

    Morning cortisol elevation makes later stress responses shorter.

    “If you spike your cortisol that way first thing in the morning, any stress you have during the day will lead to a more transient, a briefer increase in stress hormones.”

    Listen at 21:39

  8. Andrew David Hubermanon Low-angle sunlightPositive23:25

    Low-angle sunlight does not pose meaningful UV risk to skin or eyes.

    “when the sun is low in the sky, you don't have to worry about UV damage to your skin. You don't have to worry about damage to your eyes or getting cataract.”

    Listen at 23:25

  9. Andrew David Hubermanon Red light exposurePositive24:53

    Red light exposure can reduce glucose levels by approximately 20–30%.

    “It blunts glucose levels by nearly, it's somewhere between 20 and 30%, which is remarkable.”

    Listen at 24:53

  10. Andrew David Hubermanon Moderate-to-high-intensity exerciseNeutral26:06

    Moderate-to-high-intensity exercise temporarily triples cortisol levels.

    “A moderate to high-intensity exercise session, cardiovascular training or resistance training, will triple your cortisol level, but transiently.”

    Listen at 26:06

  11. Andrew David Hubermanon Dark sleep environmentPositive33:52

    Darker sleep environments reduce symptoms across several mental and neurological conditions.

    “Even just making your sleep environment darker has a significant positive effect on reducing symptoms of depression, OCD, mania, dementia, and on and on.”

    Listen at 33:52

  12. Andrew David Hubermanon Side-to-side eye movementsPositive37:21

    Side-to-side eye movements reduce amygdala activity.

    “when the eyes are moving from side to side, for whatever reason, it quiets the activity of this brain region called the amygdala”

    Listen at 37:21

  13. Andrew David Hubermanon Closed-eye movementsPositive42:10

    Specific closed-eye movements can make returning to sleep easier.

    “when you're ready to go back to sleep, do these eye movements. You will find almost certainly that you'll fall back asleep much more easily.”

    Listen at 42:10

  14. Andrew David Hubermanon Sleep apneaNegative45:25

    Sleep apnea increases risks of dementia and heart attack without directly causing dementia.

    “Apnea is bad because of the buildup of carbon dioxide in sleep. It won't cause dementia, but it certainly predisposes you to it and to heart attack and so forth.”

    Listen at 45:25

  15. People should generally use nasal rather than mouth breathing.

    “As much as you can, only breathe through your mouth when eating or speaking.”

    Listen at 45:39

  16. Nasal breathing improves sleep depth and reduces apnea.

    “Your sleep is deeper. You have less apnea.”

    Listen at 47:38

  17. Andrew David Hubermanon Four-to-five hours of sleepMixed48:59

    Four to five hours of sleep permits functioning but harms long-term health.

    “you can carry on for better or worse, for quite a long while with four to five hours, but you're not setting yourself up for health in the long run.”

    Listen at 48:59

  18. Andrew David Hubermanon Adult sleep durationPositive49:37

    Most people need seven to eight hours of sleep.

    “For most people, they need somewhere between seven and eight.”

    Listen at 49:37

  19. Andrew David Hubermanon Audio during sleep onsetPositive53:16

    People who fall asleep with audio may continue using it.

    “if listening to a podcast or having the news on helps you fall asleep, I actually suggest you keep doing it.”

    Listen at 53:16

  20. Andrew David Hubermanon Non-sleep deep restPositive56:40

    Non-sleep deep rest improves sleep onset and trauma recovery.

    “people's ability to fall asleep gets better. People recover from traumatic experiences better.”

    Listen at 56:40

  21. Andrew David Hubermanon Health optimizationPositive1:02:03

    Health optimization should accommodate personal limits while maximizing vitality and enjoyment.

    “true optimization is about accepting who you are and what you are and are not going to do, and then trying to get the most vigor and enjoyment out of life”

    Listen at 1:02:03

  22. Brian Johnson’s sleep advice is valid, but his longevity lifestyle is caricatured.

    “his takeaways about sleep, I think, are very valid, but it's more of a caricature of longevity, in my opinion”

    Listen at 1:04:25

  23. Andrew David Hubermanon Clinical OCDNegative1:06:30

    Clinical OCD involves compulsions that worsen rather than relieve obsessions.

    “The clinical definition of OCD is when the compulsion, the behavior actually doesn't suppress the obsession, it makes it worse.”

    Listen at 1:06:30

  24. SSRIs substantially help people with severe OCD.

    “ssris have greatly helped people with severe ocd”

    Listen at 1:07:52

  25. Andrew David Hubermanon Smartphone proximityNegative1:11:49

    A nearby phone impairs focus more than a phone in another room.

    “if your phone is upside down on the table in front of you, or it's in your bag under your chair, completely turned off, You have a harder time focusing compared to if it's in a different room.”

    Listen at 1:11:49

  26. More outdoor exposure can reduce myopia in children.

    “If kids just take their tablets, computers outside, if you get outside more, you offset this.”

    Listen at 1:17:37

  27. Cortisol will increasingly be viewed as beneficial when high morning and low at night.

    “Cortisol will no longer be seen as this stress hormone. It will be seen as the thing to leverage high morning, low at night.”

    Listen at 1:21:22

  28. Learning improves during the four to five hours after exercise.

    “you learn so much better in the four or five hours after exercise.”

    Listen at 1:32:07

  29. Andrew David Hubermanon “If only” thinkingNegative1:35:39

    “If only” thinking is spiritually destructive.

    “two most dangerous words in the English language are if only.”

    Listen at 1:35:39

  30. Andrew David Hubermanon Expressive writingPositive1:37:01

    Four days of 15-minute expressive writing reduces emotional burden.

    “if you take 15 minutes, but just 15, not more, and you write about that four days in a row, by the end of the fourth day, you will... have significantly offloaded a lot of the emotional load of that thing.”

    Listen at 1:37:01

  31. Andrew David Hubermanon Effortless dopamine rewardsNegative1:44:35

    Rewards without effort can seriously damage human development.

    “dopamine and rewards. without effort first destroy a human it just destroys a human”

    Listen at 1:44:35

  32. Andrew David Hubermanon Physiological sighPositive1:51:59

    Physiological sighs rapidly calm people and improve sleep, mood, and cardiovascular measures.

    “the physiological sigh allows you to calm down the fastest and it improves your sleep it improves your mood and it improves resting heart rate heart rate variability.”

    Listen at 1:51:59

  33. Caffeine may reduce dementia risk.

    “The data say it can offset dementia.”

    Listen at 1:53:08

  34. Andrew David Hubermanon VapingNegative1:53:54

    Vaping causes numerous lung problems, though less harmfully than smoking.

    “vaping isn't good for you. Not as bad as smoking, but it's still terrible. Causes all sorts of lung issues.”

    Listen at 1:53:54

  35. Nicotine is highly habit-forming and addictive.

    “nicotine is extremely habit forming slash addicting.”

    Listen at 1:54:40

  36. Nicotine raises blood pressure and can harm men’s cardiovascular and sexual health.

    “it also raises blood pressure, which in particular for men can cause cardiovascular issues and sexual health issues because it's a blood flow inhibitor”

    Listen at 1:54:54

  37. Andrew David Hubermanon Nicotine useMixed1:56:22

    Nicotine users should monitor blood pressure and exercise.

    “if you're going to use nicotine, make sure you check your blood pressure. And ideally, you're exercising too.”

    Listen at 1:56:22

  38. Andrew David Hubermanon CannabisNegative1:58:32

    Young males should avoid cannabis.

    “young males should not use cannabis.”

    Listen at 1:58:32

  39. Andrew David Hubermanon CannabisNegative1:58:43

    Cannabis generally inhibits motivation and success.

    “Cannabis, except for extremely talented creatives, is a motivation success inhibitor.”

    Listen at 1:58:43

  40. Andrew David Hubermanon Unhealthy lifestyleNegative1:59:55

    Doing everything wrong while remaining healthy is very unlikely.

    “The data say that's very unlikely.”

    Listen at 1:59:55

  41. Andrew David Hubermanon Daily wellness protocolPositive2:02:53

    Morning light, breathing, and dark sleep conditions quickly improve overall wellbeing.

    “if you do those three things, you will find that everything gets better right away.”

    Listen at 2:02:53

  42. Andrew David Hubermanon Daily wellness protocolPositive2:03:26

    Following the recommended wellness practices improves health and longevity.

    “you will be healthier, you will live longer.”

    Listen at 2:03:26

Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.

Books & mentions

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Huberman turns health optimization into sustainable daily habits · PodLume