The Dr. Hyman Show
The Dr. Hyman Show

Nov 11, 2026 · 1h 20m

Ultra-processed food may reshape the developing brain

What If Your Diet Is Affecting Your Brain More Than You Think? | Michael Goran, PhD

The conversation connects early exposure to processed food with brain development, metabolic health, and disease risk before obvious changes in body weight appear.

3 key takeaways
  1. 1Ultra-processed diets may affect brain structure and development even before differences in weight or diabetes emerge.
  2. 2Prenatal and childhood exposure combines missing protective nutrients with additives, altered food structures, and possible microbiome disruption.
  3. 3Reducing liquid sugar, cooking more from scratch, and improving school meals offer practical routes toward healthier food environments.

Don't miss

Goran describes findings in six-year-olds linking higher ultra-processed food consumption with lower subcortical brain volume before weight differences appear.

The brief

Michael Goran, PhD, frames ultra-processed food as a developmental issue: nutrition from pregnancy through childhood may influence the brain as well as metabolism.

The episode examines a central tension in food policy: researchers see broad health signals, while industry opposition and definitional disputes complicate action.

Goran discusses research in six-year-olds associating higher ultra-processed food intake with lower subcortical brain volume, even without weight differences.

Sugary drinks emerge as the clearest target because rapidly absorbed liquid sugar delivers a metabolic burden linked to fatty liver disease, inflammation, and diabetes.

The practical response is less about perfection than access: reduce liquid sugar, cook more from scratch, and make healthier school and home food affordable.

Books & mentions

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